The Effects of a Mindfulness-Based Intervention on Emotional Distress, Quality-of-Life, and HbA1c in Outpatients With Diabetes (DiaMind): A randomized controlled trial

OBJECTIVE

Emotional distress is common in outpatients with diabetes, affecting ~20–40% of the patients. The aim of this study was to determine the effectiveness of group therapy with Mindfulness-Based Cognitive Therapy (MBCT), relative to usual care, for patients with diabetes with regard to reducing emotional distress and improving health-related quality-of-life and glycemic control.

RESEARCH DESIGN AND METHODS

In the present randomized controlled trial, 139 outpatients with diabetes (type 1 or type 2) and low levels of emotional well-being were randomized to MBCT (n = 70) or a waiting list group (n = 69). Primary outcomes were perceived stress (Perceived Stress Scale), anxiety and depressive symptoms (Hospital Anxiety and Depression Scale), mood (Profiles of Mood States), and diabetes-specific distress (Problem Areas In Diabetes). Secondary outcomes were health-related quality-of-life (12-Item Short-Form Health Survey), and glycemic control (HbA1c). Assessments were conducted at baseline and at 4 and 8 weeks of follow-up.

RESULTS

Compared with control, MBCT was more effective in reducing stress (P < 0.001, Cohen d = 0.70), depressive symptoms (P = 0.006, d = 0.59), and anxiety (P = 0.019, d = 0.44). In addition, MBCT was more effective in improving quality-of-life (mental: P = 0.003, d = 0.55; physical: P = 0.032, d = 0.40). We found no significant effect on HbA1c or diabetes-specific distress, although patients with elevated diabetes distress in the MBCT group tended to show a decrease in diabetes distress (P = 0.07, d = 0.70) compared with the control group.

CONCLUSIONS

Compared with usual care, MBCT resulted in a reduction of emotional distress and an increase in health-related quality-of-life in diabetic patients who had lower levels of emotional well-being.

The Effects of a Mindfulness-Based Intervention on Emotional Distress, Quality-of-Life, and HbA1c in Outpatients With Diabetes (DiaMind): A randomized controlled trial

OBJECTIVE

Emotional distress is common in outpatients with diabetes, affecting ~20–40% of the patients. The aim of this study was to determine the effectiveness of group therapy with Mindfulness-Based Cognitive Therapy (MBCT), relative to usual care, for patients with diabetes with regard to reducing emotional distress and improving health-related quality-of-life and glycemic control.

RESEARCH DESIGN AND METHODS

In the present randomized controlled trial, 139 outpatients with diabetes (type 1 or type 2) and low levels of emotional well-being were randomized to MBCT (n = 70) or a waiting list group (n = 69). Primary outcomes were perceived stress (Perceived Stress Scale), anxiety and depressive symptoms (Hospital Anxiety and Depression Scale), mood (Profiles of Mood States), and diabetes-specific distress (Problem Areas In Diabetes). Secondary outcomes were health-related quality-of-life (12-Item Short-Form Health Survey), and glycemic control (HbA1c). Assessments were conducted at baseline and at 4 and 8 weeks of follow-up.

RESULTS

Compared with control, MBCT was more effective in reducing stress (P < 0.001, Cohen d = 0.70), depressive symptoms (P = 0.006, d = 0.59), and anxiety (P = 0.019, d = 0.44). In addition, MBCT was more effective in improving quality-of-life (mental: P = 0.003, d = 0.55; physical: P = 0.032, d = 0.40). We found no significant effect on HbA1c or diabetes-specific distress, although patients with elevated diabetes distress in the MBCT group tended to show a decrease in diabetes distress (P = 0.07, d = 0.70) compared with the control group.

CONCLUSIONS

Compared with usual care, MBCT resulted in a reduction of emotional distress and an increase in health-related quality-of-life in diabetic patients who had lower levels of emotional well-being.

A Single Nucleotide Polymorphism Associates With the Response of Muscle ATP Synthesis to Long-Term Exercise Training in Relatives of Type 2 Diabetic Humans

OBJECTIVE

Myocellular ATP synthesis (fATP) associates with insulin sensitivity in first-degree relatives of subjects with type 2 diabetes. Short-term endurance training can modify their fATP and insulin sensitivity. This study examines the effects of moderate long-term exercise using endurance or resistance training in this cohort.

RESEARCH DESIGN AND METHODS

A randomized, parallel-group trial tested 16 glucose-tolerant nonobese relatives (8 subjects in the endurance training group and 8 subjects in the resistance training group) before and after 26 weeks of endurance or resistance training. Exercise performance was assessed from power output and oxygen uptake (Vo2) during incremental tests and from maximal torque of knee flexors (MaxTflex) and extensors (MaxText) using isokinetic dynamometry. fATP and ectopic lipids were measured with 1H/31P magnetic resonance spectroscopy.

RESULTS

Endurance training increased power output and Vo2 by 44 and 30%, respectively (both P < 0.001), whereas resistance training increased MaxText and MaxTflex by 23 and 40%, respectively (both P < 0.001). Across all groups, insulin sensitivity (382 ± 90 vs. 389 ± 40 mL ⋅ min–1 ⋅ m–2) and ectopic lipid contents were comparable after exercise training. However, 8 of 16 relatives had 26% greater fATP, increasing from 9.5 ± 2.3 to 11.9 ± 2.4 μmol ⋅ mL–1 ⋅ m–1 (P < 0.05). Six of eight responders were carriers of the G/G single nucleotide polymorphism rs540467 of the NDUFB6 gene (P = 0.019), which encodes a subunit of mitochondrial complex I.

CONCLUSIONS

Moderate exercise training for 6 months does not necessarily improve insulin sensitivity but may increase ATP synthase flux. Genetic predisposition can modify the individual response of the ATP synthase flux independently of insulin sensitivity.

Short- and Long-Term Effects of Real-Time Continuous Glucose Monitoring in Patients With Type 2 Diabetes

OBJECTIVE

To determine whether short-time, real-time continuous glucose monitoring (RT-CGM) has long-term salutary glycemic effects in patients with type 2 diabetes who are not on prandial insulin.

RESEARCH DESIGN AND METHODS

This was a randomized controlled trial of 100 adults with type 2 diabetes who were not on prandial insulin. This study compared the effects of 12 weeks of intermittent RT-CGM with self-monitoring of blood glucose (SMBG) on glycemic control over a 40-week follow-up period. Subjects received diabetes care from their regular provider without therapeutic intervention from the study team.

RESULTS

There was a significant difference in A1C at the end of the 3-month active intervention that was sustained during the follow-up period. The mean, unadjusted A1C decreased by 1.0, 1.2, 0.8, and 0.8% in the RT-CGM group vs. 0.5, 0.5, 0.5, and 0.2% in the SMBG group at 12, 24, 38, and 52 weeks, respectively (P = 0.04). There was a significantly greater decline in A1C over the course of the study for the RT-CGM group than for the SMBG group, after adjusting for covariates (P < 0.0001). The subjects who used RT-CGM per protocol (≥48 days) improved the most (P < 0.0001). The improvement in the RT-CGM group occurred without a greater intensification of medication compared with those in the SMBG group.

CONCLUSIONS

Subjects with type 2 diabetes not on prandial insulin who used RT-CGM intermittently for 12 weeks significantly improved glycemic control at 12 weeks and sustained the improvement without RT-CGM during the 40-week follow-up period, compared with those who used only SMBG.

Optimizing Insulin Glargine Plus One Injection of Insulin Glulisine in Type 2 Diabetes in the ELEONOR Study: Similar effects of telecare and conventional self-monitoring of blood glucose on patient functional health status and treatment satisfaction

OBJECTIVE

To determine the functional health status and treatment satisfaction in patients with type 2 diabetes from the Evaluation of Lantus Effect ON Optimization of use of single dose Rapid insulin (ELEONOR) study that investigated whether a telecare program helps optimization of basal insulin glargine with one bolus injection of insulin glulisine.

RESEARCH DESIGN AND METHODS

Functional health status and treatment satisfaction were investigated using the 36-Item Short-Form (SF-36) Health Survey, the World Health Organization Well-Being Questionnaire (WBQ), and the Diabetes Treatment Satisfaction Questionnaire.

RESULTS

Of 291 randomized patients, 238 completed the study (telecare: 114; self-monitoring blood glucose: 124). Significant improvements were detected in most SF-36 domains, in WBQ depression and anxiety scores, and in treatment satisfaction, without differences between study groups.

CONCLUSIONS

An insulin regimen that substantially improves metabolic control, while minimizing the risk of hypoglycemia, can positively affect physical and psychologic well-being and treatment satisfaction irrespective of the educational support system used.

Side Effects of Happy

So…  This past week has been one of the happiest I’ve had in a very long time.  The promise of what’s to come seems full force and I’m enjoying every second of the here and now.

 

And it’s effect on my bloodsugar has been, in short, stunning.  

 

I have had two out of range bloodsugars in seven days.  Now, my control is decent, but this is more than a little unusual.  

 

I was trying to recall today the last time I’d had a week like this bloodsugar wise.  Looking back at my sugarstats page, it would appear that was over four years ago.  Four years ago, I was in a job I loved, in a stable long-term relationship, that particular week I was in San Francisco for work and enjoying the company of some long lost friends.  I was eating well, I was walking everywhere.  Physically and mentally, I felt good – I felt happy.  

 

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Dealing With Diabetes – Symptoms of Hypoglycemia

Hypoglycemia is a considerable challenge for most with diabetes because it prevents many folks from maintaining a normal blood glucose level. Diabetics can keep their blood glucose levels low enough to prevent long term complications such as vision related problems, kidney disease and nerve disorders, but the issue of avoiding heart disease requires an even lower level of blood glucose which is very difficult to maintain because of the threat of hypoglycemia. This is especially true for folks with type 1 diabetes. A normal blood glucose level runs between 80 and 140 mg/dl. The issue here is that hypoglycemia starts at just below 80 mg/dl, but symptoms may not present themselves until your blood glucose drops below 60 mg/dl.

Looking for some good news here? You’re in luck because most folks recover completely from the effects of hypoglycemia.

Hypoglycemia can be a tricky situation to avoid because of the medication that is prescribed to you in order to lower your glucose levels. Your body simply doesn’t operate well when your blood glucose levels are too low. So many components need glucose to function properly. Your brains needs it to operate the rest of your body as well as to allow you to function on an intellectual level. You muscles also need the energy provided by glucose much in the same way your motorcycle needs gas to operate.

When your body senses that its blood glucose levels are too low, hormones are released in an attempt to raise your glucose levels. But a problem arises. Remember that medication you are on to push your glucose levels down? Well, they keep the hormones from doing their job. Sometimes, especially when you have just begun a new medication regiment, you may be more susceptible to hypoglycemia. It may take some adjustments, but eventually you will get the medication adjusted and things will be back to normal again.

So what is the blood glucose level that you will develop hypoglycemia? Most experts agree that a blood glucose level of 60 mg/dl or less is the point where most show will symptoms of hypoglycemia. However, all people are different. As discussed earlier, some will show symptoms at a much higher level.

Most doctors break the symptoms of hypoglycemia into two major categories:

1. Symptoms tied to the side effects of the increase in hormones (specifically epinephrine) triggered by your body to counter the glucose lowering effect of insulin. This category is referred to as adrenergic symptoms, named so due to the fact epinephrine comes from your adrenal gland.

2. Symptoms that are tied to your brain not receiving enough glucose so that you are unable to function intellectually. This category is referred to as neuroglycopenic symptoms. This is the medical term for not enough (penic) glucose (glyco) in the brain (neuro).

So, let’s get to the symptoms.

Adrenergic symptoms will normally manifest themselves when your blood glucose falls quickly. These symptoms are tip offs that you are either hypoglycemic, or are on the verge of becoming so in the very near future:

1. Excessive Hunger
2. Irritability
3. Whiteness of your skin
4. Numbness in your lips, toes or fingers
5. Rapid heartbeat
6. Anxiety
7. Palpitations, or the sensation that your heart is beating way too fast

Neuroglycopenic symptoms generally occur when it takes longer for your hypoglycemia to develop. Symptoms will get progressively more severe as your blood glucose level drops. These symptoms are often tip offs that you are already hypoglycemic or will be very shortly:

1. Poor color vision
2. Headache
3. Hearing troubles
4. Double or blurred vision
5. Trouble concentrating or state of confusion
6. Loss of concentration
7. Coma, or inability to be awoken
8. Feeling of warmth
9. Slurred speech
10. Convulsions

It is very easy to tell when an intelligent person is hypoglycemic because they will make uncharacteristic simple mistakes. They may also appear to be drunk.

If you are taking insulin, it’s really important that you carry your ID with you at all times in case you develop hypoglycemia. Of course, you can always wear a Medicalert bracelet or other jewelry that indicates your condition.

Scott has been writing articles online since 2007. He began writing about diabetes when his dad was diagnosed at that time. In addition to his writing, Scott also operates a number of informative web sites. You can check out his latest website on the Hidden Wall Safe featuring Fireproof Wall Safes

Author: Scott Graves
Article Source: EzineArticles.com
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The Metabolic Syndrome

Do you find yourself having trouble losing weight even with exercise and, for all intents and purposes, watching what you eat? I suspect that you have been told to eat a low fat, high carbohydrate diet and you have done that. So why is there still a problem? You probably have thought of every possible reason for your lack of success. You may have thought that your thyroid gland is not working properly or your metabolism has slowed down: probably not. Possibly your hormone levels are off or maybe you need to step up your exercise program, or maybe you need one of these more dramatic diets to go on: not likely. That sounded like me and how I was thinking.

Normal Energy Production And Storage

You may or may not have been aware of something called “The Metabolic Syndrome.” What is it, you may ask? Allow me to give you a little background of basic information before I define this syndrome.

Our bodies need fuel for energy just like any machine. Sugar is that source. We need to get down to the cellular level where this energy production actually occurs. Glucose is the sugar utilized by the cell for the production of energy in the furnaces of our cells, which are called mitochondria. The entry of glucose into the cells is facilitated by the hormone insulin, which is produced in the pancreas. This hormone also will drive glucose into muscle and the liver for storage in a more complex form called glycogen. This will be used as a source of energy at other times such as periods of starvation and exercise. Any amounts over and above normal usage for immediate energy and storage in liver and muscle are sent to fat cells for greater storage of energy sources.

There is an opposing hormone, glucagon, which is also produced in the pancreas and is responsible for releasing fat for energy when stimulated by the intake of protein. The intake of carbohydrates and excessive levels of insulin suppress it.

Normally these hormones work in conjunction with each other maintaining a balanced situation of energy substrates utilization and storage. Situations such as dieting, starvation, exercise and the Metabolic Syndrome will alter this balance.

Glycemic Index

Whenever we ingest sugar or carbohydrates our bodies react with a rise in the blood sugar inducing the secretion of insulin to get the sugar into our cells and produce energy and store the excess in muscle, the liver, and eventually, fat. The Glycemic Index is a measurement of the rate of the rise of blood sugar following the ingestion of a particular test food relative to that of a standard food such as glucose. The measurement for glucose is 100. This index will quantitate the rate of secretion of insulin. Under 55 is generally considered to be a low-glycemic food and over 70 is high-glycemic.

Low GI = 55 or less

Medium GI = 56 – 69

High GI = 70 or more

Our diet today is mainly composed of over-processed carbohydrates in the form of our modern-day flour. This flour is the result of removing all of its complex components, leaving us with a pure, super-fine white powder that, when ingested, causes our blood sugar to rise rapidly to higher than normal levels. This leads to an exaggerated insulin response. This rapid rise in insulin will cause blood sugar levels to drop precipitously to relatively low levels, lower than normal, causing drowsiness, and fatigue. The subsequent rebound also results in a desire to eat again to restore blood sugar levels. Long term this becomes an uncontrollable craving for carbohydrates. This roller coaster effect occurring over and over, leads to carbohydrate addiction, carbohydrate craving, nighttime eating, insulin resistance, and the beginning of the Metabolic Syndrome. These high insulin levels also shut off the glucagon response and leave no way that fat can be utilized as a source of energy. This is when weight gain occurs and weight loss becomes almost impossible.

Eventually, this syndrome will cause inflammation and narrowing of the small arteries going to the muscles of your body causing them to constrict. This leads to a decreased ability of insulin to deliver glucose to the muscles for use and storage. Insulin levels will then increase significantly to try and accomplish this task but, eventually, most of the glucose will be diverted to fat cells causing what is called “insulin resistance.” Glucagon is totally shut off at this point.

Some of the other effects of the Metabolic Syndrome are high blood pressure, increased triglyceride and cholesterol levels, and decreased HDL, all leading to an increased risk of cardiovascular disease. This Syndrome has been said to occur in about 20-25% of the population. A significant portion of this group will go from insulin resistance to full blown Diabetes as the Metabolic Syndrome causes a “burn-out” of the insulin-producing cells of the pancreas. This is also one of the reasons why we are seeing a lot more obesity and diabetes, especially in our young. It is getting to epidemic proportions.

Low-Glycemic Response

There is hope! There is an answer. It is called a low glycemic diet. This must be considered a lifestyle change, not a temporary eating habit. Traditional diets do not work because they are designed to be an acute solution to a chronic problem. Also the faster one loses weight, generally, the faster it comes back. The chances of losing up to 10% of your total body weight and keeping it off for 5 years is the same as the 5 year survival rate for cancer of the lung, 5%. This is a very sobering statistic. You will find that it may, and should, take 18-24 months for you to achieve your end results. You should set short-term goals along the way. I have actually chosen to let my body decide what its end-point will be and take as long as it needs to get there since my program also involves exercising, which yours should too.

You need to understand that this syndrome is reversible with time while the alternative of not making this change is diabetes, which is never reversible. Remember, if you continue to do what you have always done, you will continue to get what you have always gotten.

When an individual eats a low-glycemic meal there is a totally different metabolic response. Eating foods such as fruits, vegetables, good carbs that do not cause a rapid rise of your blood sugar, good protein and fat is the answer. The “whites” are out: the white breads, the white potato, and the white rice. Even most whole wheat bread is not our friend. It cannot be enriched wheat flour; it must be stone ground.

These types of carbs will allow a slow rise of blood sugar, leading to a more modest release of insulin balanced with a proper release of glucagon. The insulin encourages the muscle to take up the sugar and the rest goes to the liver and fat. On the other hand, glucagon is also present in normal levels and will break down the fat, at about the same rate it is created, initially at a greater rate. The result of this equation is no weight gain or possible weight loss. Even if you have the Metabolic Syndrome, the start of a low glycemic lifestyle, not diet, may allow a reversal of all of the bad effects of this syndrome. Eventually, exercise must become a part of this healthy lifestyle.

Conclusions

So how do we summarize this complex bit of information and put it into a useful tool that is easy to follow. First of all, how badly do you want the results, the goals that you set? If the goal is important enough the work will follow and you will accomplish it. Remember that the Metabolic Syndrome is reversible with time, and Diabetes is never reversible.

Here are some general guidelines to follow. Low glycemic food will not raise your blood sugar as high and as rapidly as high glycemic foods will and, at the same time, will start to increase your body’s sensitivity to insulin. Low glycemic diets will help you to lose weight, help those who already have diabetes maintain better control of their blood sugar. Low glycemic foods will help you to stay full longer. Finally, high glycemic foods may replenish carbohydrate stores after exercise but low glycemic foods will improve physical endurance.

Foods that have a low glycemic index generally had a low glycemic load. Eliminate foods with both high glycemic indexes and high glycemic loads. Optimize your insulin levels by eating fruits and vegetables and whole grains. The fiber in these foods will both be healthy and release sugar into your bloodstream slowly.

I want to reiterate for you that I have changed my lifestyle to low-glycemic index, low glycemic load and have seen a significant change in myself. I am not hungry all the time anymore. I am free of carbohydrate addiction and cravings. I can actually sit in front of the TV at night or read a book and not have a high-glycemic snack next to me. I have not been doing it long enough to get off all of my meds but I see that in the near future and I recently was able to reduce my high blood pressure medication. Remember, getting healthy is a process and this is just one of the steps. It is not about what has happened to me, but I do know this can work for you.

I am not saying that this is the lifestyle change that you have to make, but if you see yourself in a similar situation, take a good look. Obviously you will need to discuss this with your doctor and see if it is a fit for you. You should also work out a program with your personal physician to regularly check your labs, weight, and blood pressure. Remember, if you continue doing what you are doing, you will continue to have what you have. If you want to make some changes in your life, you must make some changes in your life. I wish you success and good health.

Dr Zelem is the author of the book “The Process of Becoming Healthy” contains a detailed explanation of this syndrome and is available for seminars. Visit http://www.streamlineintelligence.com, email jz@streamlineintelligence.com or call 866-222-4884

Author: John D Zelem, MD
Article Source: EzineArticles.com
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Know More About Insulin

Type 1 diabetes mellitus patient always uses insulin. Insulin is also used by a type 2 patient in some conditions. These conditions includes rapid lose of body weight, high increase of blood sugar (severe hyperglycemia), ketoacidosis and failure use of oral hypoglycemic agent in almost maximal dose.

The main function of insulin is to maintain the blood sugar in normal rate. Insulin works this way: it engages with the insulin receptor which lies in the surface of a cell. This complex makes the sugar being deposited in the cell from the blood so there will be no excessive sugar in the blood circulation.

If the function is disturbed, glucose is not permeated, remain to stay in the blood. As a result glucose amount in blood is rising. The condition can generate various negative effects, such as blood vessel damage, till damage of many organs, such as kidney, eye, brain, and other organ.

Insulin regimens

Insulin will be digested by digestion system, so it cannot be given orally. It should be administered in the form of injection subcutaneously (below/under the skin). Here are some regimens:

* Ultra short-acting insulin: very rapid onset (15 minutes) and short duration (5 hours), for example: Insulin lispro (Humalog), Insulin aspart (Novolog), insulin glulisine (Apidra).

* Short-acting Insulin: onset between 30-60 minutes and last for 6-8 hours. Some of the regimens are: Actrapid, Humulin S

* Intermediate-Acting Insulin: isophane insulin starts to work after two hours and lasts for 10-14 hours. This kind includes Humulin I, Insulatard, NPH Novolin and Lente Iletin.

* Long-Acting Insulin: slow onset (one or two hours), and last for 24 hours. The examples are zinc suspension (Hypurin Bovine Lente), protamine zinc insulin (Hypurin Bovine protamine zinc), glargine analog (Lantus) And insulin detemir (Levemir).

* Biphasic insulin: combination of short-acting and intermediate-acting insulin in different dose proportion, e.g. 30/70, 50/50 (NovoMix 30, Humulin M3, Hypurin porcine 30/70).

Insulin Inhalation.

Insulin inhalation is now already available. You just have to inhale this kind of drug, the same as asthma drugs. It is easier and more comfortable for the patient because he/she does not need injection. Insulin Inhalation cannot be administered to patient of lung disease, such as asthma, or chronic obstructive pulmonary disease. The procedure and type will be determined by the physician considering patient’s desire and life style.

Pregnancy and Breastfeeding

Insulin delivered into placenta will not disturb the foetus growth. During pregnancy blood sugar rate have to be maintained, to avoid pregnancy disorders. At early pregnancy, insulin dose usually will be degraded, while at second and third trimester its dose will be boosted up.

Insulin will not be secreted to milk, so it is safe for a mother to breastfeed her baby. During breastfeeding, dose is lessened. Doctor will give the suggestion about it.

Any Safarodiyah is a medical doctor. She developed http://www.waytobehealth.com to help others learn to do the best for their health. To receive tons of info, tips, about our health for free visit http://www.waytobehealth.com

Author: Any Safarodiyah
Article Source: EzineArticles.com
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Types of Insulin Used to Treat Diabetes

There are different types of insulin using to treat Diabetes. These types of insulin are categorized for rapid action. These types are for short, intermediate and long term.

The brand names of rapid action insulin are Novo Log, Apidra, and Humalog, and their chemical names include insulin aspart, glulisine, and lispro respectively.

Short-term or short acting insulin is Humulin-R as brand name and the chemical name is insulin regular.

You can find intermediate acting insulin, of which the brand name is Humulin and the chemical name is insulin NPH.

The long acting insulin for diabetes can be Levemir, and Lantus as the brand names and the chemical names of these products are insulin detemir and glargine respectively.

The premixed rapid- and intermediate-acting insulin can be 70% intermediate acting (NPH) and 30% short-acting regular insulin, called 70/30 insulin. Similarly, the 50/50 insulin is 50% intermediate acting (NPH) and 50% short-acting regular insulin, the 75/25 insulin is 75% intermediate-acting and 25% rapid-acting Humalog (lispro), the Novo Log or 70/30 pre-mixed insulin is 70% intermediate-acting and 30% rapid-acting Novo Log (insulin aspart,) and this insulin is available.

Insulin is to treat type 1 diabetes and type 2 diabetes. People who are suffering from type 2 diabetes and their pancreas produces little or no insulin or their oral medication does not work properly or does not control blood sugar can take insulin or can take along with oral medication. Due to major surgery and severe illness with high-level blood sugar, type 2 diabetics can stop taking insulin if the blood sugar level returns to the target level.

Women along with type 2 diabetes are pregnant or in breast feeding mode, they cannot keep their blood sugar levels within a target range with diet and exercise; only one oral diabetes medicine, glyburide has been studied and recommended for use during pregnancy. Unless the further research takes place, American Diabetes Association suggests that pregnant women and breast-feeding women do not take oral diabetes medicines.

Insulin is effective to reduce sugar levels. It helps blood sugar (glucose) enter the cells for energy consumption. The 10-year study reveals Diabetes Control and Complications Trial, DCCT and followed up Epidemiology of Diabetic Interventions and Complications, EDIC notice that people with type 1 diabetes can control the blood sugar levels within normal or near the normal range (tightly controlled therapy), and fewer incidence of eye, kidney or nerve damage from diabetes than standard therapy.

Tightly controlled therapy lowered the risks of heart disease and death. Another one study shows that insulin glargine (Lantus), is as effective as NPH insulin does control blood sugar of type 1 diabetics. Lantus can create fewer low blood sugar episodes than NPH2.

Side Effects – The major side effect of insulin can be a dangerously low blood sugar level (severe hypoglycemia). The very low blood sugar level can develop within 10 to 15 minutes with rapid acting insulin. Insulin can contribute to type 2 diabetes for weight gain.

Find Diabetes Natural Treatment to control sugar level. Find powerful Libido Enhancer to boost your lovemaking performance.

Author: Dr Andrew Napier
Article Source: EzineArticles.com
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